S. Merkelbach-Bruse: search on Z-Library

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1

Tumours from MSH2 mutation carriers show loss of MSH2 expression but many tumours from MLH1 mutation carriers exhibit weak positive MLH1 staining

Elisabeth Mangold, Constanze Pagenstecher, Waltraut Friedl, Hans-Peter Fischer, Sabine Merkelbach-Bruse, Maike Ohlendorf, Nicolaus Friedrichs, Stefan Aretz, Reinhard Buettner, Peter Propping, Micaela

Journal:

The Journal of Pathology

Year:

2005

Language:

english

File:

PDF, 326 KB

english, 2005

2

Immune profile and immunosurveillance in treatment-naive and neoadjuvantly treated esophageal adenocarcinoma

Wagener-Ryczek, Svenja, Schoemmel, Max, Kraemer, Max, Bruns, Christiane, Schroeder, Wolfgang, Zander, Thomas, Gebauer, Florian, Alakus, Hakan, Merkelbach-Bruse, Sabine, Buettner, Reinhard, Loeser, Hei

Journal:

Cancer Immunology, Immunotherapy

Year:

2020

Language:

english

File:

PDF, 1.93 MB

english, 2020

3

β-Catenin ( CTNNB1 ) mutations and clinicopathological features of mesenteric desmoid-type fibromatosis

Huss, Sebastian, Nehles, Julia, Binot, Elke, Wardelmann, Eva, Mittler, Jens, Kleine, Michaela Angelika, Künstlinger, Helen, Hartmann, Wolfgang, Hohenberger, Peter, Merkelbach-Bruse, Sabine, Buettner,

Journal:

Year:

2013

Language:

english

File:

PDF, 751 KB

english, 2013

4

The impact of sequencing on diagnosis and treatment of malignant melanoma

Castiglione, Roberta, Ihle, Michaela A, Heydt, Carina, Schultheis, Anne M, Merkelbach-Bruse, Sabine, Mauch, Cornelia, Büttner, Reinhard

Journal:

Expert Review of Molecular Diagnostics

Year:

2016

Language:

english

File:

PDF, 1.41 MB

english, 2016

5

A Novel Germline KIT Mutation (p.L576P) in a Family Presenting With Juvenile Onset of Multiple Gastrointestinal Stromal Tumors, Skin Hyperpigmentations, and Esophageal Stenosis

Neuhann, Teresa M., Mansmann, Veit, Merkelbach-Bruse, Sabine, Klink, Barbara, Hellinger, Achim, Höffkes, Heinz-Gert, Wardelmann, Eva, Schildhaus, Hans-Ulrich, Tinschert, Sigrid

Journal:

American Journal of Surgical Pathology

Year:

2013

Language:

english

File:

PDF, 382 KB

english, 2013

6

Monitoring treatment response to erlotinib in EGFR-mutated non-small cell lung cancer brain metastases using serial O-(2-[18F]fluoroethyl)-L-tyrosine PET

Abdulla, Diana S.Y., Scheffler, Matthias, Brandes, Vanessa, Ruge, Maximilian, Kunze, Sabine, Merkelbach-Bruse, Sabine, Nogova, Lucia, Michels, Sebastian, Fischer, Rieke, Riedel, Richard, Büttner, Rein

Journal:

Clinical Lung Cancer

Year:

2018

Language:

english

File:

PDF, 875 KB

english, 2018

7

147PImpact on KRAS-subtypes and TP53 mutations on the prognostic value of KRAS/KEAP1 comutations in non-small cell lung cancer (NSCLC)

Scheffler, M, Frank, R, Ihle, M A, Abdulla, D S, Koleczko, S, Nogova, L, Holzem, A, Chanra, T, Riedel, R, Michels, S, Fischer, R N, Kron, A, Merkelbach-Bruse, S, Buettner, R, Wolf, J

Journal:

Annals of Oncology

Year:

2019

Language:

english

File:

PDF, 73 KB

english, 2019

8

Nuclear hBD-1 accumulation in malignant salivary gland tumours

M Wenghoefer, A Pantelis, H Dommisch, W Götz, R Reich, S Bergé, M Martini, JP Allam, S Jepsen, S Merkelbach-Bruse, HP Fischer, N Novak, J Winter

Journal:

Year:

2008

Language:

english

File:

PDF, 1.28 MB

english, 2008

9

Therapeutic strategies in male breast cancer: Clinical implications of chromosome 17 gene alterations and molecular subtypes

Schildhaus, Hans-Ulrich, Schroeder, Lars, Merkelbach-Bruse, Sabine, Binot, Elke, Büttner, Reinhard, Kuhn, Walther, Rudlowski, Christian

Journal:

Year:

2013

Language:

english

File:

PDF, 407 KB

english, 2013

10

Diagnostik gastrointestinaler Stromatumoren

Wardelmann, E., Merkelbach-Bruse, S., Büttner, R., Hohenberger, P., Schildhaus, H.-U.

Journal:

TumorDiagnostik & Therapie

Year:

2010

Language:

german

File:

PDF, 565 KB

german, 2010

11

K-ras Mutation Subtypes in NSCLC and Associated Co-occuring Mutations in Other Oncogenic Pathways

Scheffler, Matthias, Ihle, Michaela A., Hein, Rebecca, Merkelbach-Bruse, Sabine, Scheel, Andreas H., Siemanowski, Janna, Brägelmann, Johannes, Kron, Anna, Abedpour, Nima, Ueckeroth, Frank, Schüller, M

Journal:

Journal of Thoracic Oncology

Year:

2018

Language:

english

File:

PDF, 1.08 MB

english, 2018

12

Molekulardiagnostik von Mutationen des epidermalen Wachstumsfaktor-Rezeptors und Aktivierung nachgeschalteter Signalwege in nichtkleinzelligen Lungenkarzinomen

Lukas C. Heukamp, Sebastian Zimmer, Philip Kahl, Sabine Merkelbach-Bruse, Reinhard Buettner

Journal:

Year:

2008

Language:

german

File:

PDF, 1.10 MB

german, 2008

13

Prevalence of cytomegalovirus in nonrheumatic stenotic aortic valves

Peter W Radke, Jan R Ortlepp, Sabine Merkelbach-Bruse, Bruno J Messmer, Axel Kaiser, Stephan Kronenberger, Stefan Handt, Peter Hanrath

Journal:

The American Journal of Cardiology

Year:

2002

Language:

english

File:

PDF, 56 KB

english, 2002

14

Anaplastic lymphoma kinase (ALK) gene rearrangement in non-small cell lung cancer (NSCLC): Results of a multi-centre ALK-testing

v. Laffert, Maximilian, Warth, Arne, Penzel, Roland, Schirmacher, Peter, Jonigk, Danny, Kreipe, Hans, Schildhaus, Hans-Ulrich, Merkelbach-Bruse, Sabine, Büttner, Reinhard, Reu, Simone, Kerler, Rosi, J

Journal:

Year:

2013

Language:

english

File:

PDF, 1.55 MB

english, 2013

15

Comparison of high resolution melting analysis, pyrosequencing, next generation sequencing and immunohistochemistry to conventional Sanger sequencing for the detection of p.V600E and non-p.V600EBRAFmutations

Ihle, Michaela, Fassunke, Jana, König, Katharina, Grünewald, Inga, Schlaak, Max, Kreuzberg, Nicole, Tietze, Lothar, Schildhaus, Hans-Ulrich, Büttner, Reinhard, Merkelbach-Bruse, Sabine

Journal:

Year:

2014

Language:

english

File:

PDF, 1.33 MB

english, 2014

16

Targeting TKI-resistance in NSCLC: Importance of rebiopsy and molecular diagnostics—A case study

Stoehlmacher-Williams, Jan, Ehninger, Gerhard, Zimmermann, Dieter R., Merkelbach-Bruse, Sabine, Schildhaus, Hans-Ulrich, Buettner, Reinhard

Journal:

Cancer Treatment Communications

Year:

2013

Language:

english

File:

PDF, 738 KB

english, 2013

17

Erblicher Darmkrebs (HNPCC): eine wichtige Diagnose auch im höheren Lebensalter

Friedrichs, Nicolaus, Rahner, Nils, Friedl, Waltraut, Steinke, Verena, Merkelbach-Bruse, Sabine, Propping, Peter, Büttner, Reinhard, Walldorf, Constanze

Journal:

Gastroenterologie up2date

Year:

2006

Language:

german

File:

PDF, 321 KB

german, 2006

18

Multiple gastrointestinale Stromatumoren – Metastasen oder Koinzidenz?

Majores, Michael, Fassunke, Jana, Merkelbach-Bruse, Sabine, Büttner, Reinhard, Wardelmann, Eva

Journal:

Gastroenterologie up2date

Year:

2009

Language:

german

File:

PDF, 298 KB

german, 2009

19

HR23b expression is a potential predictive biomarker for HDAC inhibitor treatment in mesenchymal tumours and is associated with response to vorinostat

Angelika Ihle, Michaela, Merkelbach-Bruse, Sabine, Hartmann, Wolfgang, Bauer, Sebastian, Ratner, Nancy, Sonobe, Hiroshi, Nishio, Jun, Larsson, Olle, Åman, Pierre, Pedeutour, Florence, Taguchi, Takahir

Journal:

The Journal of Pathology Clinical Research

Year:

2016

Language:

english

File:

PDF, 573 KB

english, 2016

20

Epidermal growth factor receptor mutations in non-small cell lung cancer influence downstream Akt, MAPK and Stat3 signaling

Sebastian Zimmer, Philip Kahl, Theresa M. Buhl, Susanne Steiner, Eva Wardelmann, Sabine Merkelbach-Bruse, Reinhard Buettner, Lukas C. Heukamp

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2009

Language:

english

File:

PDF, 546 KB

english, 2009

21

Expression and Function of β1 and β3 Integrins of Human Mesothelial Cells in vitro

Lothar Tietze, Jana Bornträeger, Bernd Klosterhalfen, Baffour Amo-Takyi, Stefan Handt, Kalle Günther, Sabine Merkelbach-Bruse

Journal:

Experimental and Molecular Pathology

Year:

1999

Language:

english

File:

PDF, 425 KB

english, 1999

22

Wees voorbereid

Ihle, Michaela, Fassunke, Jana, König, Katharina, Grünewald, Inga, Schlaak, Max, Kreuzberg, Nicole, Tietze, Lothar, Schildhaus, Hans-Ulrich, Büttner, Reinhard, Merkelbach-Bruse, Sabine

Journal:

Year:

2012

Language:

dutch

File:

PDF, 97 KB

dutch, 2012

23

LSD1 modulates the non-canonical integrin β3 signaling pathway in non-small cell lung carcinoma cells

Lim, So-Young, Macheleidt, Iris, Dalvi, Priya, Schäfer, Stephan C., Kerick, Martin, Ozretić, Luka, Ortiz-Cuaran, Sandra, George, Julie, Merkelbach-Bruse, Sabine, Wolf, Jürgen, Timmermann, Bernd, Thoma

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 5.56 MB

english, 2017

24

27PComparison of three different gene panels for determination of tumor mutational burden by next generation sequencing

Pappesch, R, Heydt, C, Rehker, J, Merkelbach-Bruse, S

Journal:

Annals of Oncology

Year:

2019

Language:

english

File:

PDF, 80 KB

english, 2019

25

Gastrointestinal stromal tumors carrying PDGFRα mutations occur preferentially in the stomach and exhibit an epithelioid or mixed phenotype

E. Wardelmann, K. Pauls, S. Merkelbach-Bruse, A. Hrychyk, I. Losen, P. Hohenberger, R. Büttner, T. Pietsch

Journal:

Pathology - Research and Practice

Year:

2004

Language:

english

File:

PDF, 152 KB

english, 2004

26

Pitfalls in mutational testing and reporting of commonKITandPDGFRAmutations in gastrointestinal stromal tumors

Sabine Merkelbach-Bruse, Wolfgang Dietmaier, Laszlo Füzesi, Andreas Gaumann, Florian Haller, Julia Kitz, Antje Krohn, Gunhild Mechtersheimer, Roland Penzel, Hans-Ulrich Schildhaus, Regine Schneider-St

Journal:

BMC Medical Genetics

Year:

2010

Language:

english

File:

PDF, 1.25 MB

english, 2010

27

Fibroblast growth factor receptor 1 gene amplification in pancreatic ductal adenocarcinoma

Lehnen, Nils C, von Mässenhausen, Anne, Kalthoff, Holger, Zhou, Hui, Glowka, Tim, Schütte, Ute, Höller, Tobias, Riesner, Katarina, Boehm, Diana, Merkelbach-Bruse, Sabine, Kirfel, Jutta, Perner, Sven,

Journal:

Year:

2013

Language:

english

File:

PDF, 593 KB

english, 2013

28

Consensus Polymerase Chain Reaction and Enzyme-Linked Immunosorbent Assay for Human Papillomavirus Detection and Typing in Cervical Specimens

Merkelbach-Bruse, Sabine, Jakob, Christiane, Tietze, Lothar, Schröder, Willibald, Rath, Werner, Füzesi, Laszlo

Journal:

Diagnostic Molecular Pathology

Year:

1999

File:

PDF, 595 KB

1999

29

Gastrointestinale Stromatumoren des Magens

E. Wardelmann, P. Hohenberger, P. Reichardt, S. Merkelbach-Bruse, H.-U. Schildhaus, R. Büttner

Journal:

Year:

2010

Language:

german

File:

PDF, 414 KB

german, 2010

30

c-KITcodon 816 mutation in a recurrent and metastatic dysgerminoma of a 14-year-old girl: case study

Katharina Pauls, Eva Wardelmann, Sabine Merkelbach-Bruse, Reinhard Büttner, Hui Zhou

Journal:

Virchows Archiv

Year:

2004

Language:

english

File:

PDF, 264 KB

english, 2004

31

PDGFRα- and c-kit-mutated gastrointestinal stromal tumours (GISTs) are characterized by distinctive histological and immunohistochemical features

K Pauls, S Merkelbach-Bruse, D Thal, R Büttner, E Wardelmann

Journal:

Year:

2005

Language:

english

File:

PDF, 655 KB

english, 2005

32

High-Resolution Melting Analysis as a Sensitive Prescreening Diagnostic Tool to Detect KRAS, BRAF, PIK3CA, and AKT1 Mutations in Formalin-Fixed, Paraffin-Embedded Tissues

Ney, Jasmin Teresa, Froehner, Stefanie, Roesler, Angelika, Buettner, Reinhard, Merkelbach-Bruse, Sabine

Journal:

Archives of Pathology & Laboratory Medicine

Year:

2012

Language:

english

File:

PDF, 2.69 MB

english, 2012

33

Pitfalls in the Detection of t(11;22) Translocation by Fluorescence In Situ Hybridization and RT-PCR: A Single-blinded Study

Friedrichs, Nicolaus, Kriegl, Lydia, Poremba, Christopher, Schaefer, Karl-Ludwig, Gabbert, Helmut Erich, Shimomura, Akihiko, Paggen, Ellen, Merkelbach-Bruse, Sabine, Buettner, Reinhard

Journal:

Diagnostic Molecular Pathology

Year:

2006

Language:

english

File:

PDF, 268 KB

english, 2006

34

3129 Clinical and genetic presentation of high-level cMET-amplified Non-small cell lung cancer (NSCLC) with adenocarcinoma histology

Eisert, A., Scheffler, M., Frank, R., Gogl, L., Scheel, A., Merkelbach-Bruse, S., Michels, S., Fischer, R., Büttner, R., Wolf, J.

Journal:

European Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 60 KB

english, 2015

35

Implementing TMB measurement in clinical practice: considerations on assay requirements

Büttner, Reinhard, Longshore, John W, López-Ríos, Fernando, Merkelbach-Bruse, Sabine, Normanno, Nicola, Rouleau, Etienne, Penault-Llorca, Frédérique

Journal:

Year:

2019

File:

PDF, 1.26 MB

2019

36

„Benign metastasizing leiomyoma“ ? a cytogeneticly balanced but monoclonal disease

L. Tietze, K. Günther, S. Merkelbach-Bruse, S. Handt, Ch. Mittermayer

Journal:

Biomedicine & Pharmacotherapy

Year:

1998

Language:

english

File:

PDF, 147 KB

english, 1998

37

Acquired resistance to imatinib in gastrointestinal stromal tumours caused by multiple KIT mutations

Eva Wardelmann, Nadja Thomas, Sabine Merkelbach-Bruse, Katharina Pauls, Nicola Speidel, Reinhard Büttner, Heiner Bihl, Claudia C Leutner, Thomas Heinicke, Peter Hohenberger

Journal:

The Lancet Oncology

Year:

2005

Language:

english

File:

PDF, 163 KB

english, 2005

38

Definition of a fluorescence in situ hybridization score identifies high- and low-level FGFR1 amplification types in squamous cell lung cancer

Schmitz, Katja, Schildhaus, Hans-Ulrich, Heukamp, Lukas Carl, Merkelbach-Bruse, Sabine, Wolf, Jürgen, Buettner, Reinhard

Journal:

Year:

2012

Language:

english

File:

PDF, 48 KB

english, 2012

39

Gastrointestinal Stromal Tumors With KIT Exon 9 Mutations

Künstlinger, Helen, Huss, Sebastian, Merkelbach-Bruse, Sabine, Binot, Elke, Kleine, Michaela Angelika, Loeser, Heike, Mittler, Jens, Hartmann, Wolfgang, Hohenberger, Peter, Reichardt, Peter, Büttner,

Journal:

American Journal of Surgical Pathology

Year:

2013

Language:

english

File:

PDF, 544 KB

english, 2013

40

Expression of cell cycle regulators and frequency of TP53 mutations in high risk gastrointestinal stromal tumors prior to adjuvant imatinib treatment

Ihle, Michaela Angelika, Huss, Sebastian, Jeske, Wiebke, Hartmann, Wolfgang, Merkelbach-Bruse, Sabine, Schildhaus, Hans-Ulrich, Büttner, Reinhard, Sihto, Harri, Sundby Hall, Kirsten, Eriksson, Mikael,

Journal:

Year:

2018

Language:

english

File:

PDF, 9.92 MB

english, 2018

41

132PNew insights into acquired resistance mechanisms to third-generation EGFR tyrosine kinase inhibitor therapy in lung cancer

Fassunke, J, Heydt, C, Michels, S, Veggel, B Van, Müller, F, Keul, M, Dammert, M A, Schmitt, A, Smit, E F, Kast, S, Wolf, J, Buettner, R, Sos, M L, Rauh, D, Merkelbach-Bruse, S

Journal:

Annals of Oncology

Year:

2019

Language:

english

File:

PDF, 75 KB

english, 2019

42

1308PRET TRANSLOCATION IN ADENOCARCINOMA OF THE LUNG

Michels, S., Schultheis, A., Scheffler, M., Rosner, T., Merkelbach-Bruse, S., Heukamp, L.C., Engel-Riedel, W., Serke, M., Krüger, S., Benedikter, J., Gerigk, U., Schulte, W., Draube, A., Ko, Y., Büttn

Journal:

Annals of Oncology

Year:

2014

File:

PDF, 61 KB

2014

43

qPCR in gastrointestinal stromal tumors: Evaluation of reference genes and expression analysis ofKITand the alternative receptor tyrosine kinasesFLT3,CSF1-R,PDGFRB,METandAXL

Jana Fassunke, Marie-Christine Blum, Hans-Ulrich Schildhaus, Marc Zapatka, Benedikt Brors, Helen Künstlinger, Reinhard Büttner, Eva Wardelmann, Sabine Merkelbach-Bruse

Journal:

BMC Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1.06 MB

english, 2010

44

Relevanz molekularpathologischer Befunde für die Diagnose, Prognose und Therapie von gastrointestinalen Stromatumoren

Eva Wardelmann, Sabine Merkelbach-Bruse, Reinhard Büttner, Peter Hohenberger, Peter Reichardt, Hans-Ulrich Schildhaus

Journal:

Year:

2008

Language:

german

File:

PDF, 251 KB

german, 2008

45

Prevalence of Chlamydia pneumoniae in nonrheumatic stenotic aortic valves

Radke, Peter W., Ortlepp, Jan R., Merkelbach-Bruse, Sabine, Kaiser, Axel, Kronenberger, Stephan, Handt, Stefan, Hanrath, Peter

Journal:

American Heart Journal

Year:

2002

Language:

english

File:

PDF, 46 KB

english, 2002

46

Inflammatorische fibroide Polypen des Magen-Darm-Trakts

S. Huss, H. Schildhaus, S. Merkelbach-bruse, E. Wardelmann, R. Büttner

Year:

2008

Language:

german

File:

PDF, 131 KB

german, 2008

47

Chromogenic in situ hybridization is a reliable assay for detection of ALK rearrangements in adenocarcinomas of the lung

Schildhaus, Hans-Ulrich, Deml, Karl-Friedrich, Schmitz, Katja, Meiboom, Maren, Binot, Elke, Hauke, Sven, Merkelbach-Bruse, Sabine, Büttner, Reinhard

Journal:

Modern Pathology

Year:

2013

Language:

english

File:

PDF, 331 KB

english, 2013

48

Implementing amplicon-based next generation sequencing in the diagnosis of small cell lung carcinoma metastases

Meder, Lydia, König, Katharina, Fassunke, Jana, Ozretić, Luka, Wolf, Jürgen, Merkelbach-Bruse, Sabine, Heukamp, Lukas C., Buettner, Reinhard

Journal:

Experimental and Molecular Pathology

Year:

2015

Language:

english

File:

PDF, 611 KB

english, 2015

49

MET Gene Copy Number Alterations and Expression of MET and Hepatocyte Growth Factor Are Potential Biomarkers in Angiosarcomas and Undifferentiated Pleomorphic Sarcomas

Schmitz, Katja, Koeppen, Hartmut, Binot, Elke, Fassunke, Jana, Künstlinger, Helen, Ihle, Michaela A., Heydt, Carina, Wardelmann, Eva, Büttner, Reinhard, Merkelbach-Bruse, Sabine, Rüschoff, Josef, Schi

Journal:

Year:

2015

Language:

english

File:

PDF, 3.03 MB

english, 2015

50

Deletion of Trp-557 and Lys-558 in the juxtamembrane domain of the c-kit protooncogene is associated with metastatic behavior of gastrointestinal stromal tumors

Eva Wardelmann, Inge Losen, Volkmar Hans, Iris Neidt, Nicola Speidel, Erhard Bierhoff, Thomas Heinicke, Torsten Pietsch, Reinhard Büttner, Sabine Merkelbach-Bruse

Journal:

International Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 407 KB

english, 2003

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